【单选题】
（2）Formulation is about the design, development and evaluation of dosage forms,___
A. discovery of novel drugs
B. analytical methods
C. drug delivery systems and manufacturing process
D. dosing regimen
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答案
C
解析
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相关试题
【单选题】
(3)Biopharmaceutics mainly studies the in vivo process of drugs and metabolites in humans, animals and tissue culture, which specifically involves___
A. absorption and distribution
B. absorption, distribution, metabolism, and excretion
C. metabolism and excretion
D. absorption and excretion
【单选题】
(4)Regarding the definition of bioavailability(BA), BA is related to___
A. total plasma drug concentration only
B. unbound drug concentration in the plasma
C. unbound drug concentration at the target site
D. total plasma drug concentration, and the administered drug dose
【单选题】
(5)Plasma drug concentration is affected by following factors such as___
A. rate of absorption
B. rate and extent of distribution
C. rate ofeli Imination
D. all ofabove
【单选题】
6)Which of the following routes of administration will involve the absorption of drugs?___
A. i.v.injection
B. i.v.infusion
C. Subcutaneous injection, transdermal and oral
D. None of above
【单选题】
（7）Which of the following factors may influence the time course of a drug in the plasma and hence at its site of action?___
A. Food
B. Disease state
C. Route of administration
D. All of above
【单选题】
(8)Please identify the potential biological barriers for an orally administered tablet to be absorbed into the systemic circulation___
A. Sk d dermis
B. Gastrointestinal epithelium
C. Oral mucosal membrane
D. All of above
【单选题】
(9) Given the same administration dose, which of the following will likely result in varying bioavailabilities for the same drug administered to the same person? ___
A. tablets (p.o. )vs. solutions(p0.)
B. solutions for injection(i v )vs oral solutions(p0.)
C. coated tablets (p.0. )vs hard gelatin capsules(p0.)
D. All ofabove
【单选题】
(10)Which of the following statements is true?___
A. Bioavailability is only related to the administered dose and the total drug concentration in the blood circulation.
B. Plasma protein binding does not affect the bioavailability of a specific drug.
C. A given drug in different dosage forms may show differences in bioavailability if given by the same route.
D. Biopharmaceutical studies do not involve animal experiment.
【判断题】
Much of our present physiological knowledge has been found from the experiments and studies on human beings.
A. 对
B. 错
【判断题】
Living cells break down glucose and fats to provide energy for other activities, which is called.
A. 对
B. 错
【判断题】
The right atriapumps deoxygenated blood to the lungs where it absorbs oxygen from the air.
A. 对
B. 错
【判断题】
The nervous system uses electrical signals to transmit information very rapidly to specific cells.
A. 对
B. 错
【判断题】
With the level of sodium increasing extracelular fruid. the cardiac muscle cells become too excitable and may contract.
A. 对
B. 错
【判断题】
A negative feedback loop is a control system that acts to maintain the level of some variables within a given range following a disturbance
A. 对
B. 错
【判断题】
(1)Pharmacodynamics, which is concerned with the study of the biochemical and physiological effects of drugs and their mechanisms of action, Is an experimental medical science.
A. 对
B. 错
【判断题】
2)It's unreasonable for a physician to be interested mainly in the effects of drugs on human beings, for the pharmacological evaluation of drugs in them may be limited due to technical, legal, and ethical reasons.
A. 对
B. 错
【判断题】
（3） As the effects of drugs are often characterized by significant interspecies variation and may be further modified by disease, clinical pharmacology has never been efibrasized.
A. 对
B. 错
【判断题】
The physician is not interested in drugs that are useful in the prevention,diagnosis,and treatment of human disease, but in chemical agents that are commonly responsible for household and industrial poisoning as well as environmental pollution.
A. 对
B. 错
【判断题】
(5)A drug is said to be useful in therapy if it has the ability to produce its desired effects with only tolerable undesired effects.
A. 对
B. 错
【判断题】
(6)Toxicology deals not only with drugs used in therapy but also with many other chemicals that may be responsible for household, environmental, or industrial intoxication.
A. 对
B. 错
【判断题】
1)With the more efficient screening tests and burgeoning knowledge about how a molecules biological activities are likely to be changed, the traditional approach of discovering new drugs has been improved.
A. 对
B. 错
【判断题】
2)With the parallel synthesis used to identify which small segment of any given large protein would bind to an antibody, Mario Geysen generated a variety of short protein fragments by combining multiple amino acids in different permutations.
A. 对
B. 错
【判断题】
)A parallel synthesis and a split-and-mix synthesis are different in that in a split-and-mix synthesis, all the products are assembled separately n their respective reaction vessels.
A. 对
B. 错
【判断题】
4) In many laboratories, robots are used in the routine work of parallel synthesis to deliver small amounts of reactive molecules into appropriate wells, thus making the process more accurate and less tedious.
A. 对
B. 错
【判断题】
5) In a parallel synthesis, each compound remains in its own container; while in a split-and-min synthesis, the related ce mpounds are mixed up in the same reaction vessel.
A. 对
B. 错
【判断题】
6)In order to solve the difficulties of identifying the compounds made in a parallel synthesis scientists pull out from the mixture the beads that bear biologically active molecules and determine the molecular makeup o d attached.
A. 对
B. 错
【判断题】
1)The concentration of a drug in whole plasma is the most accurate index of the drug concentration at the site（s） of action.
A. 对
B. 错
【判断题】
(2)It is difficult to measure the total concentration of both unbound and bound drug in total plasma.
A. 对
B. 错
【判断题】
(3)The clinical effect of a drug is assumed to be directly related to the plasma drug concentration.
A. 对
B. 错
【判断题】
(4) Systemically acting drugs administered by all routes involve the absorption of drug from the place of administration into the blood.
A. 对
B. 错
【判断题】
5)Bioavailability of a drug indicates whether a therapeutically effective concentration is achieved at the site(s)of action of that drug.
A. 对
B. 错
【判断题】
(6)Prodrugs are not therapeutically effective unless they are changed into therapeutically active forms before or after reaching the systemic circulation
A. 对
B. 错
【单选题】
（3）生物圈的范围为___
A. 大气圈、水圈和岩石圈的全部
B. 大气圈和水圈的全部、岩石圈的上部
C. 大气圈的底部、水圈和岩石圈的全部
D. 大气圈的底部、水圈的全部和岩石圈的上部
【单选题】
（8）地球的表面积约为5.1亿平方千米，表面起伏不平，凸出来的地方成为陆地和山脉，而大片大片下凹的部分经过亿万年的积累，被液态海水所淹没而变成了海洋，海洋面积占地球表面积的近___。
A. 2％
B. 51%
C. 71%
D. 91%
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接触网值班员接到维修中心生产调度准备抢修通知后：___
A. 通知当值工班工班长立即出动抢修；
B. 通知维修中心值班司机，出动事故抢修汽车；
C. 通知接触网备班工班长；
D. 通知主管工程师；
E. 参加抢修工作，并记录关键时间及事故信息（事故地点、事故
【多选题】
在进行隔离开关倒闸作业时，应如何办理倒闸作业手续？___
A. 操作人受令复诵，电力调度员确认无误后，方可给命令编号和批准时间
B. 先由操作人向电力调度提出申请，电力调度员审查后，发布倒闸作业命令(如果是DCC管理的隔离开关，则到DCC办理倒闸手续)；
C. 每次倒闸作业，发令人要将命令内容等记入“倒闸操作命令记录”中；
D. 操作完毕后，受令人要填写“隔离开关倒闸完成报告单”
【多选题】
下列说法正确的是___
A. 湾厦备用线由2X03供电臂供电
B. 科苑存车线由2S05供电臂供电
C. 安托山存车线由2X08供电臂供电
D. 福田存车线由2X08供电臂供电。
【多选题】
到达事故现场后属于抢修组长的行动内容有___
A. 接触网故障点的查找
B. 收集故障设备资料
C. 进入现场检查设备损坏情况，如发现接触网故障导致其他系统 设备破坏，必须及时向 OCC 行调汇报详细情况，由行调协调处理；
D. 以先通后复的原则制定事故抢修方案，尽快恢复列车运行
【多选题】
检测系统运行过程中，软件出现异常，不能正常检测。 下列处理意见正确的有___
A. 检查各检测主机通信是否正常。
B. 检查各检测主机检测软件运行是否正常，并进行重启软件；
C. 检查硬件设备相应指示灯是否正常
D. 按压检测观察窗“紧急降弓”按钮，执行降弓
【多选题】
OCC行车调度接到事故消息后___
A. 发布抢修命令，协调相关车站按照现场抢修组长要求开放出入口并布置进入轨行区的抢修路径
B. 根据事故现场需求调动接触网作业车组到达现场，通报相关配合抢修作业负责人的信息
C. 如发生电客车弓网故障，通知车辆抢修队出动抢修
D. 根据抢修现场负责人的要求调动相邻车辆段接触网工班支援
【多选题】
下列选项中关于后海停车场供电分区和每个分区分别由那几个上网隔离开关供电说法正确的有___
A. 后海停车场共分ABCD4个供电分区
B. 后海停车场共分ABC3个供电分区
C. C区由2131隔离开关供电
D. D区由2131隔离开关供电
【多选题】
下列选项中关于蛇口西车辆段供电分区和每个分区分别由那几个上网隔离开关供电说法正确的有___
A. 蛇口西车辆段共分ABCDEF6个供电分区
B. 蛇口西车辆段共分ABCDE5个供电分区
C. C区由2141隔离开关供电
D. D区由2141隔离开关供电
【多选题】
下列选项中正确的有___
A. 后海入场线是海月站—海上世界站下行2X03供电臂供电
B. 后海出场线是海上世界站—海月站下行2S03供电臂供电
C. 背对赤湾往新秀方向右线为上行，上行悬挂点以R字母开头每两个车站间编一系列号码，从赤湾侧往新秀方向递增编码
D. 背对赤湾往新秀方向左线为下行；下行悬挂以L字母开头每两个车站间编一系列号码，从赤湾侧往新秀方向递增编码
【多选题】
下列关于隔离开关故障处理程序说法正确的有___
A. 上网隔离开关损坏或上网电缆故障时可合越区隔离开关，实现越区供电行车；
B. 越区隔离开关损坏时，如不影响行车，运营结束后处理；
C. 电动隔离开关电动拒合闸时，立即出动抢修找出隔开故障处理完故障后恢复行车；
D. 承担单边供电的上网隔离开关损坏时，用电连接线将绝缘关节短接
【多选题】
下列关于隧道漏水故障处理程序正确的是___
A. 漏水至汇流排上，造成接触网无法送电时，加装汇流排防水罩。
B. 检查汇流排及绝缘子状态良好后撤离，并上报维修调度，通知工建专业进行隧道堵漏。
C. 漏水造成绝缘子击穿时，更换绝缘子并加装绝缘子防水罩。
D. 漏水为对汇流供电造成影响时记录位置。
【多选题】
通过平面布置图，可以直接提取哪些设备数据信息___，其中（ D ）可以查阅相关图纸获得。
A. 导高
B. 拉出值
C. 隧道资料
D. 设备安装形式和悬挂形式
E. 锚段长度
F. 设备安装位置
